Have a question about parasites or FRONTLINE® products?

Check out the FAQ page.


  • Do fleas & ticks need to bite my pet to be killed by (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus)?

    No, Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) act topically which means that fleas and ticks are killed through contact with your pet's skin and coat. They do not need to bite to be killed.

  • Why is it also important to tackle flea eggs?

    Even if you have treated your pet for fleas, some fleas may still have time to lay eggs before dying. These eggs can develop into new fleas in as little as 14 days. Therefore, it is important to tackle flea eggs too. Most flea products only kill fleas on your pet, Fipronil + (S)-Methoprene (FRONTLINE® Plus), not only kills fleas and ticks on your pet but also prevents flea eggs from hatching & developing.

  • Is Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) safe to use on my pet?

    Yes. Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) have an exemplary safety profile in dogs & cats. Adverse reactions to the treatments are very rare. If you believe your pet has experienced any side effects from a veterinary medicinal product, please contact your trusted veterinarian.

  • Why might I still see fleas on my treated pet?

    If you can still see fleas on your pet after treating them, it would be natural to think that the treatment isn’t working. However, no product can repel fleas from jumping onto your pet so it is normal to continue to see fleas after treatment as your pet can pick up new fleas from the environment at any time. Moreover, if you are fighting a home infestation, it is highly likely to see fleas on your pet for 3 months or more as it can take this long to get rid of the infestation. Don't worry, if you see fleas for several days in a row, today's flea is not the one you saw yesterday. Your treated pet is a flea-killing machine and any fleas jumping on will be killed within 24 hours.

  • How does (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) work?

    Once applied, Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) are stored in the sebaceous glands in your pet's skin and spreads over the whole-body surface with their natural oils. Fleas and ticks are killed through contact with your pet's skin and coat, so they do not need to bite to be killed.

  • Why might I still see ticks on my treated pet?

    Most tick treatments such as Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) are not tick repellents therefore individual ticks may still attach to your pet. After treatment with Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus), ticks will generally be killed within 48 hours after exposure, before they are fully fed, thus helping to reduce the risk of disease transmission.

  • What is the difference between (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus)?

    Both products kill fleas and ticks in dogs & cats, however our more advanced formula, Fipronil + (S)-Methoprene (FRONTLINE® Plus), also stops flea eggs from hatching & developing.

  • Do I need to treat my pet for fleas and ticks during warm months?

    Yes. Tropical countries like the Philippines present an ideal environment for the fleas and ticks to be active and reproduce.

  • Can Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) be used in any breed of cat & dog?

    Yes. Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) can be used on any breed of cat and dog, including collies and other herding-breed dogs which can sometimes show hypersensitivity to some parasite treatments.

  • Do I need to treat my pets for fleas & ticks even in colder or rainy months?

    Yes. Fleas also continue to develop outdoors thanks to our year-long warm & humid temperatures in the Philippines. Therefore, it’s important to keep protecting your pet throughout the year. Using Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) allows you to protect both your pet & home from flea and tick infestation.

  • My pet is pregnant/lactating, can I use FRONTLINE® Spray & FRONTLINE®

    Yes, Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) are licensed for use in pregnant and lactating cats and dogs. 

  • My pets don’t go outdoors much, do I still need to treat them for fleas & ticks?

    Yes. Even indoor-only pets can become exposed to fleas & ticks if an untreated pet visits your home or if you or a friend brings in flea eggs or cocoons on your shoes or clothing.


  • Can I use Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) products to pets other than cats & dogs?

    Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) can only be used on dogs & cats. Do not use on rabbits and other animals.

  • Can I apply FRONTLINE® products to pets other than cats and dogs?

    You should only ever use products on pet species that they have been specifically developed and licensed for. FRONTLINE® Plus can only be used on dogs, cats and ferrets and FRONTLINE® Spray on dogs and cats only. Do not use on rabbits.

  • How do I use Fipronil (FRONTLINE® Spray) in dogs & cats?
    • 1. It is recommended to wear personal protective equipment (PPE) such as gloves & face mask prior to application.
    • 2. For 100 ml bottle, remove the cap & press down to spray; for 250 ml bottle, rotate the applicator nozzle to deliver a cone spray.
    • 3. Determine the total number of spray pumps based on the actual weight and condition of the animal then divide it into five locations (see table from product use guide). Spray 10-20 cm away from the animal. 
    • 4. Using your hand, gently rub to effectively spread it on the coat & skin of the animal after spraying.
    • 5. For sensitive areas such as the head, you can spray in a clean cloth or on your hand covered with PPE then rub it gently while avoiding contact with the eyes, nose and mouth.
    • 6. Allow the skin & coat to dry. 
    • 7. Re-apply following a monthly interval.

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  • How do I use Fipronil + (S)-Methoprene (FRONTLINE® Plus) in dogs & cats?
    • 1. It is recommended to wear personal protective equipment (PPE) such as gloves prior to application.
    • 2. Remove the pipette from the pack & its blister.
    • 3. Hold the pipette upright facing away from you, tap the neck to ensure that the contents are in the main body then snap off the tip along the scored line.
    • 4. Part the fur of the animal at the base of the neck & gently apply directly onto the skin in 1 spot. 
    • 5. The treatment will naturally spread over their skin. It is important not to bath or let the animal swim for 2 days after application.
    • 6. Re-apply following a monthly interval.

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  • Do I need to wash my pet before application of Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus)?

    Provided your pet's coat is clean, there is no specific need to wash your pet. If you do wash your pet, it is important to ensure that the coat and skin are completely dry & there is enough natural oil before applying Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus).

  • What happens if my pet gets wet straight after applying FRONTLINE® Spray & FRONTLINE® Plus?

    Once Fipronil (FRONTLINE® Spray) & Fipronil + (S)-Methoprene (FRONTLINE® Plus) has been applied, it is recommended to keep your pet out of the rain and away from watercourses for the next 48 hours. If they do come into contact with rain within this period, it is unlikely that your pet would have been wet enough for the product to be washed away. However, if your pet gets soaked to the skin then the efficacy of the treatment may be impaired, and reapplication may be warranted. If this is the case, please contact your veterinarian for advice.